On my current project we are running Spark on top of Yarn. Since Hadoop causes dependency problems and feels a bit ancient I was looking for an alternative. At JPoint we have a few a days a year to try things out, this was one of them. I paired with Eelco to get things up and running.
This article will show you how to run Spark on top of Mesos on your Mac (or Linux and probably a combination of these two).